There are a lot of useful features in Visual Studio, but you often do not know what you do not know.
For example, one of the questions I fielded recently was how to stop Visual Studio from stealing focus when you hit a break point. The idea being that a developer more interested in say, the graphics produced by her app, may not want Visual Studio jumping to the foreground when you hit a break point.
To change this go to Tools –> Options and select Debugging > General options. Scroll down until you find the Bring Visual Studio to the foreground when breaking in the debugger and unselect it (selected by default).
More generally my advice is to check the General > Debugging list (which updates periodically) for the selections that make the most sense for the way you want to use Visual Studio.